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Books by Terry Kenakin
  | | A Pharmacology Primer(5th Edition) Techniques for More Effective and Strategic Drug Discovery by Terry Kenakin Paperback, 488 Pages, Published 2018 by Academic Press ISBN-13: 978-0-12-813957-8, ISBN: 0-12-813957-9 "A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discover ..." |
 | | Quantitative Molecular Pharmacology and Informatics in Drug Discovery(1st Edition) by Michael William Lutz, Terry Kenakin, Terrence P. Kenakin Hardcover, 428 Pages, Published 2000 by Wiley ISBN-13: 978-0-471-98861-8, ISBN: 0-471-98861-8 "Quantitative Molecular Pharmacology and Informatics in Drug Discovery Michael Lutz, Section Head, Cheminformatics Group and Terry Kenakin, Principal Research Scientist, Glaxo Wellcome Research and Development, Research Triangle Park, NC, USA Quantitative Molecular Pharmacology and Informatics in Drug Discovery combines pharmacology, genetics and statistics to provide a complete guide to the modern drug discovery process. The book discus ..." |
 | | Pharmacology for Chemists(1st Edition) Drug Discovery in Context by Raymond Hill, Terry Kenakin, Tom Blackburn, Humphrey Rang, Fiona Marshall, Gareth Sanger, Phil Jeffrey, Munir Pirmohamed, Malcolm Boyce, Shane Gad Cox, Rsc Publishing Hardcover, 524 Pages, Published 2017 by Royal Society Of Chemistry ISBN-13: 978-1-78262-142-3, ISBN: 1-78262-142-3 "Assuming little previous knowledge of biology, this book aids graduate chemists to close the gap in their knowledge of pharmacology and make the link between medicinal chemistry and the way in which drugs act on the body. The availability of receptor structures has revolutionized drug discovery and development necessitating an up-to-date source of information for chemists entering this new pharmacological world.Chapters, written by expe ..." |
 | | A Pharmacology Primer, Second Edition(2nd Edition) Theory, Applications, and Methods by Terry Kenakin, Terrence P. Kenakin Paperback, 318 Pages, Published 2006 by Academic Press ISBN-13: 978-0-12-370599-0, ISBN: 0-12-370599-1 "The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. *Over 30 new figures and tables*More human interest information to provide readers with historical ..." |
 | | A Pharmacology Primer, Third Edition(3rd Edition) Theory, Application and Methods by Terry Kenakin Paperback, 416 Pages, Published 2009 by Academic Press ISBN-13: 978-1-4933-0112-6, ISBN: 1-4933-0112-8 "This successful guide assists scientists trained in molecular biology and related fields who now need to know the basic theories, principles and practical applications of pharmacology. This latest edition continues the tradition of better preparing researchers in the basics of pharmacology. With expanded hands-on exercises and the addition of Pharmacokinetics coverage, new human interest material including historical facts in pharmacolo ..." |
 | | Molecular Pharmacology(1st Edition) A Short Course by Terry Kenakin, Terrence P. Kenakin Paperback, 235 Pages, Published 1997 by Wiley-Blackwell ISBN-13: 978-0-86542-540-8, ISBN: 0-86542-540-X "This text provides a brief introduction to general pharmacological principles and their use as experimental tools. By using receptor theory and molecular models, this text explores the mechanisms of drug responses in body systems without using the body itself. It also discusses biostatistics as related to drug-response quantification and optimization." |
 | | Pharmacologic Analysis of Drug-Receptor Interaction by Terrence P. Kenakin, Terry Kenakin Hardcover, 491 Pages, Published 1997 by Lippincott Williams & Wilkins ISBN-13: 978-0-397-51815-9, ISBN: 0-397-51815-3 "The thoroughly revised, updated Third Edition of this highly acclaimed text reflects the past four years' groundbreaking developments in receptor pharmacology, particularly the use of human recombinant receptor systems in drug design and development. Whereas prior editions focused on the correspondence of animal to human receptor systems, this new edition examines drug effects on human receptors obtained by recombinant technology, as we ..." |
 | | Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors, Volume 115(1st Edition) (Progress in Molecular Biology and Translational Science) by Terry Kenakin Hardcover, 488 Pages, Published 2013 by Academic Press ISBN-13: 978-0-12-394587-7, ISBN: 0-12-394587-9 "In this thematic volume of Progress in Molecular Biology and Translational Science, researchers reflect on recent developments and research surrounding G protein-coupled receptors. The chapters cover a large breadth of research, including GPCR role in stem cell function and pharmacology. Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make G ..." |
 | | Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors by Terry Kenakin 488 Pages, Published 2013 by Academic Press ISBN-13: 978-0-12-394791-8, ISBN: 0-12-394791-X "Tall GG, Gilman AG. Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/ LGN/Galphai-GDP complexes. Proc Natl Acad Sci USA 2005;102:16584– 9. 156. Vellano CP, Shu FJ, Ramineni S, Yates CK, Tall GG, Hepler JR. Activation of the regulator of G protein signaling 14-Galphai1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8 ..." |
 | | A Pharmacology Primer Theory, Application and Methods by Terry Kenakin, Terrence P. Kenakin 416 Pages, Published 2009 by Academic Press ISBN-13: 978-0-08-092333-8, ISBN: 0-08-092333-X "REFERENCES 1. 10. 11. 12. 13. 14. Aguiar, A. J., Krc, J., Jr., Kinkel, A. W., and Samyn, A. C. (1967). Effect of polymorphism on the absorption of chloramphenicol from chloramphenicol palmitate. J. Pharm. Sci. 56(7):847-853. 2 . Schanker, L. S., Tocco, D. T., Brodie, B. B., and Hogben, C. A. M. (1958). Absorption of drugs from the rat small intestine. J. Pharmacol. Exp. Ther. 123:81- 88. 3. Lemke, T. L. (1992). Review of organic func ..." |
 | | A Pharmacology Primer Theory, Applications, and Methods by Terry Kenakin 318 Pages, Published 2009 by Elsevier ISBN-13: 978-0-08-046530-2, ISBN: 0-08-046530-7 "(c) Alfred. J. Clark (1885–1941). Beginning as a demonstrator in pharmacology in King's College (London), Clark went on to ... He articulated these ideas in the classic work The Mode of Action of Drugs on Cells [4], later revised as the Handbook of Experimental Pharmacology [5]. ... In this vein, prominent pharmacologists of the day such as Walter Straub (1874–1944) suggested that a general theory of ..." |
 | | A Pharmacology Primer Techniques for More Effective and Strategic Drug Discovery by Terry Kenakin 488 Pages, Published 2019 by Academic Press ISBN-13: 978-0-12-813958-5, ISBN: 0-12-813958-7 "REFERENCES. [1] A.J. Aguiar, J. Krc, A.W. Kinkel, A.C. Samyn, Effect of polymorphism on the absorption of chloramphenicol ... [4] I.A. Cates, Calculation of drug solubilities by pharmacy students, Am. J. Pharm. ... [15] T.H. Tsai, L.C. Hung, C.F. Chen, Microdialysis study of biliary excretion of chloramphenicol and its glucuronide in the rat, J. Pharm. ... antagonist with a pharmacological and pharmacokinetic profile optimized for ..." |
 | | Pharmacology in Drug Discovery and Development Understanding Drug Response by Terry Kenakin 350 Pages, Published 2016 by Academic Press ISBN-13: 978-0-12-803753-9, ISBN: 0-12-803753-9 "Understanding Drug Response Terry Kenakin ... 122 (1958) 480À488. [5] C. Ambrosio, P. Molinari, F. Fanelli, Y. Chuman, M. Sbraccia, O. Ugur, et al., Different structural requirements for the constitutive and agonist-induced activities for the β2-adrenergic receptor, J. Biol. Chem. 280 (2005) ... 87 (1954) 393À394. [ 15] J.H. Brown, G.T. Wetzel, J. Dunlap, Activation and blockage of cardiac muscarinic receptors by endogenous acetylch ..." |
 | | Allosterism in Drug Discovery(1st Edition) by Dario Doller, Terry Kenakin, Stephan Schann, Jesus Giraldo, Tom Costa, Ken Jacobsen, Stefan Knapp, Corey Hopkins, Andrew Alt, Anna-Liisa Brownell, Phil Carpino, Craig Jamieson, Mark M. Levandoski, Benny Bang-Andersen, Maurizio Botta, Shelli Mcalpine, David Thurston, David Rotella, Xinyan Huang, Sylvain Celanire, Katie Lynne Strong, Andres Trabanco, Andrés A. Trabanco, Dennis C. Liotta Hardcover, 437 Pages, Published 2016 by Royal Society Of Chemistry ISBN-13: 978-1-78262-459-2, ISBN: 1-78262-459-7 "Although the concept of allosterism has been known for over half a century, its application in drug discovery has exploded in recent years. The emergence of novel technologies that enable molecular-level ligand-receptor interactions to be studied in studied in unprecedented detail has driven this trend. This book, written by the leaders in this young research area, describes the latest developments in allosterism for drug discovery. Bri ..." |
 | | A Pharmacology Primer Theory, Application and Methods by Terry Kenakin Published 2004 ISBN-13: 978-0-08-057508-7, ISBN: 0-08-057508-0 |
 | | Drug Effects in Biological Systems by Terry Kenakin, Paul Morgan, Michael Lutz Paperback, 450 Pages, Published 1998 by Raven Pr ISBN-13: 978-0-7817-0289-8, ISBN: 0-7817-0289-5 |
 | | CP Pharmacology(Illustrated) 1 by Sam J. Enna, Michael Williams, John W. Ferkany, Terry Kenakin, Roger E. Porsolt, James P. Sullivan Hardcover, 700 Pages, Published 1998 by John Wiley & Sons Inc ISBN-13: 978-0-471-17197-3, ISBN: 0-471-17197-2 "The one-volume looseleaf manual contains concisely written protocols that guide you step-by-step through the process of characterizing new compounds using receptor-binding assays (both in vitro and in isolated tissues), enzyme assays, ..." |
 | | Pharmacology in Drug Discovery(1st Edition) Understanding Drug Response by Terry P. Kenakin, Terrence P. Kenakin Paperback, 260 Pages, Published 2011 by Academic Press ISBN-13: 978-0-12-384856-7, ISBN: 0-12-384856-3 "Pharmacology: A Short Course for the Interpretation of Dose-Response Data is designed to enable the reader to interpret drug dose-response data and make mechanistic inferences at the molecular level. This unique resource bridges the gap between biochemistry and therapeutic medicine and provides simple explanations of the ways in which biological systems use basic biochemical mechanisms to produce fine chemical control of physiology. E ..." |
 | | Pharmacology in Drug Discovery and Development, Second Edition(2nd Edition) Understanding Drug Response by Terry P. Kenakin, Terrence P. Kenakin Paperback, 350 Pages, Published 2016 by Academic Press ISBN-13: 978-0-12-803752-2, ISBN: 0-12-803752-0 "Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therap ..." |
 | | Pharmacology for Chemists Drug Discovery in Context by Tom Blackburn, Terry Kenakin, Raymond Hill 524 Pages, Published 2017 by Royal Society Of Chemistry ISBN-13: 978-1-78801-245-4, ISBN: 1-78801-245-3 "J. F. White, N. Noinaj, Y. Shibata, J. Love, B. Kloss, F. Xu, J. Gvozdenovic-Jeremic , P. Shah, J. Shiloach, C. G. Tate and R. Grisshammer, Nature, 2012, 490, 508. C. H. Lee, W. Lü, J. C. Michel, A. Goehring, J. Du, X. Song and E. Gouaux, Nature , ..." |
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