Transporters in Drug Development(Reprint) Discovery, Optimization, Clinical Study and Regulation (AAPS Advances in the Pharmaceutical Sciences Series) by YuichiSugiyama, Bente Steffansen Paperback, 336 Pages, Published 2016 by Springer ISBN-13: 978-1-4939-5206-9, ISBN: 1-4939-5206-4
"Transporters in Drug Development examines how membrane transporters can be dealt with in academic–industrial drug discovery and pharmaceutical development as well as from a regulatory perspective. The book describes methods and examples of in vitro characterization of single transporters in the intestines, liver and kidneys as well as characterization of substrate overlap between various transporters. Furthermore, probes and biomarkers ..."
Transporters in Drug Development Discovery, Optimization, Clinical Study and Regulation (AAPS Advances in the Pharmaceutical Sciences Series) by YuichiSugiyama, Bente Steffansen Hardcover, 317 Pages, Published 2013 by Springer ISBN-13: 978-1-4614-8228-4, ISBN: 1-4614-8228-3
"HardCover. Pub Date :2013-01-30 Pages: 290 Language: English Publisher: Springer Transporters in Drug Development examines how membrane transporters can be dealt with in academic-industrial drug discovery and pharmaceutical development as well as from a regulatory perspective.The book describes methods and examples of in vitro characterization of single transporters in the intestines. liver and kidneys as well as characterization of sub ..."
"The absorptive transporters of the brain endothelium play an important role in
supplying essential nutrients and ... Due to their capacity they are also interesting
from a drug delivery viewpoint; however, their drug delivery potential is limited to
a certain ... Glut-1 is situated both at the luminal and abluminal membranes of the
endothelium and the transport will therefore be ... are expressed at the 15 1
Membrane Transporters i ..."
"Modelling and simulation technologies have improved dramatically over the past decade and their applications in toxicity prediction and risk assessment are of great importance. Such approaches will become increasingly necessary as industrial chemicals advance and as new pharmaceuticals enter the market. In this comprehensive discussion of predictive toxicology and its applications, leading experts express their views on the technolog ..."