Macrophages Biology and Role in the Pathology of Diseases by Subhra K. Biswas, AlbertoMantovani Hardcover, 615 Pages, Published 2014 by Springer ISBN-13: 978-1-4939-1310-7, ISBN: 1-4939-1310-7
"Alberto Mantovani, Alexandra Fucic. CHAPTER 3 Issues for Hazard Characterization of Endocrine Disrupting Chemicals: The Use of Adverse Outcome Pathways ALBERTO MANTOVANI Department of Food safety, Nutrition and Veterinary public health ..."
Macrophages Biology and Role in the Pathology of Diseases by Subhra K. Biswas, AlbertoMantovani 615 Pages, Published 2014 by Springer ISBN-13: 978-1-4939-1311-4, ISBN: 1-4939-1311-5
"Sandra E. Nicholson and Peter J. Murray. 24.1. Introduction. What is macrophage
polarization? How does STAT–Suppressors Of Cytokine Signaling (SOCS)
signaling regulate polarization? The goal of this review is to summarize current
knowledge pertinent to the second question. However, before we review the
complex cytokine-driven processes that both promote and then feedback to
inhibit polarization, we need to address the first questio ..."
"VEGF is a potent angiogenic factor as well as a monocyte attractant that
contributes to TAM recruitment. TAM promote angiogenesis and there is
evidence that inhibition of TAM recruitment plays an important role in
antiangiogenic strategies. We found that, in addition to VEGF, the angiogenic
program established by hypoxia may rely also on the increased expression of
CXCR4 by TAM and endothelial cells [138]. Intratumoral injection of ..."
"After Phase I and II studies had suggested important activity for Sunitinib in GIST
patients failing Imatinib or being intolerant ... in a 2:1 randomization (Demetri,
Van Oosterom, Garrett, Blackstein, Shah, Verweij, McArthur, Judson, Heinrich,
Morgan, ... What the data on Sunitinib also show is that there may be a whole
range of other options for treatment of GIST. ... Interestingly, this has not only lead
to better results, but e ..."
Tumor-Associated Leukocytes Pathophysiology and Therapeutic Applications (Molecular Biology Intelligenc Unit) by AlbertoMantovani Hardcover, 106 Pages, Published 1994 by R G Landes Co ISBN-13: 978-1-57059-013-9, ISBN: 1-57059-013-3
Chemokines(1st Edition) by AlbertoMantovani, H. Renz Hardcover, 208 Pages, Published 1999 by S. Karger ISBN-13: 978-3-8055-6861-6, ISBN: 3-8055-6861-4
"Chemokines are a superfamily of small proteins which play a crucial role in immune and inflammatory reactions and in viral infection. They attract and activate leukocytes and regulate diverse cellular systems and organs ranging from blood vessels to the central nervous system. This book provides an overview of the main structural and functional features of chemokines. It presents recent studies which indicate that chemokines regulate th ..."
"GongJ, Wei T, Stark RW, Jamitzky F, Heckl WM, Anders HJ, et al. Inhibition of toll-
like receptors TLR4 and 7 signaling pathways by SIGIRR: a computational
approach. J Struct Biol (2010) 169:323–30. doi:10.1016/j.jsb.2009.12.007
Drexler SK, Kong P, Inglis J, Williams RO, Garlanda C, Mantovani A, et al.
SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells
and regulates inflammation in models of rheumato ..."