"Toxicity testing is used to assess the safety or hazards presented by substances such as industrial chemicals, consumer products, and pharmaceuticals. At present, many methods involve laboratory animals. Alternative procedures, some involving human cell-based technologies, are now being developed which reduce, refine, or replace animal usage and minimize the pain and distress caused. These new tests must protect public health and the en ..."
"Today, we are surrounded by a multitude of different chemicals that are essential components of our everyday life. As a consequence, there are various hazardous substances like dioxins, phthalates and flame-retardants circulating in the environment. These have an impact on ecosystems, wildlife and possibly human health. In recent years, the phenomenon called endocrine disruption has raised considerable concern. This book discusses the s ..."
"Cytokines are polypeptide mediators which act as communication signals among cells of the immune system as well as among other cells and tissues in the body. They are a heterogeneous and complex group and include interferons, tumor necrosis factor and chemokines. They play a key role in homeostasis and in host defense and are involved in such inflammatory and autoimmune diseases such as rheumatoid arthritis as well as infectious disease ..."
"A. Kortenkamp, Ten years of mixing cocktails: A review of combination effects of endocrine-disrupting chemicals, Environ. Health Perspect., 2007, DOI: 10.1289/ehp.9357. 3. A. Kortenkamp, Low dose mixture effects of endocrine disrupters: ..."
"Padova, 2006; br., pp. 106. L'endotelio è stato concepito come un "organo diffuso" che gioca un ruoloessenziale nel regolare una varietà di processi fisiologici che vanno daltraffico omeostatico delle cellule linfoidi, all'emostasi e trombosi,all'infiammazione, all'espressione delle risposte dell'immunità adattativa edalla formazione ed organizzazione di nuovi vasi. Gli studi sulla plasticitàdell'endotelio si sono arricchiti della defin ..."
Chemokines(1stEdition) by AlbertoMantovani, H. Renz Hardcover, 208 Pages, Published 1999 by S. Karger ISBN-13: 978-3-8055-6861-6, ISBN: 3-8055-6861-4
"Chemokines are a superfamily of small proteins which play a crucial role in immune and inflammatory reactions and in viral infection. They attract and activate leukocytes and regulate diverse cellular systems and organs ranging from blood vessels to the central nervous system. This book provides an overview of the main structural and functional features of chemokines. It presents recent studies which indicate that chemokines regulate th ..."