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  | | Pharmacology of Cytokines(1st Edition) by Alberto Mantovani, Charles A. Dinarello, Pietro Ghezzi, Petro Ghezzi Paperback, 329 Pages, Published 2000 by Oxford University Press ISBN-13: 978-0-19-850042-1, ISBN: 0-19-850042-4 "Cytokines are polypeptide mediators which act as communication signals among cells of the immune system as well as among other cells and tissues in the body. They are a heterogeneous and complex group and include interferons, tumor necrosis factor and chemokines. They play a key role in homeostasis and in host defense and are involved in such inflammatory and autoimmune diseases such as rheumatoid arthritis as well as infectious disease ..." |
 | | Macrophages Biology and Role in the Pathology of Diseases by Subhra K. Biswas, Alberto Mantovani Hardcover, 615 Pages, Published 2014 by Springer ISBN-13: 978-1-4939-1310-7, ISBN: 1-4939-1310-7 "Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morpho ..." |
 | | Targeted Therapies in Cancer(Reprint) Myth or Reality? (Advances in Experimental Medicine and Biology) by Francesco Colotta, Alberto Mantovani Paperback, 200 Pages, Published 2010 by Springer ISBN-13: 978-1-4419-2537-4, ISBN: 1-4419-2537-6 "Billions of dollars are spent every year on research into targeted therapies for cancer. That's why it's more than ever crucial for the thousands of scientists working in the field to keep right up to date with the cutting edge. This fascinating collection of material goes a long way to helping them do so, featuring as it does contributions to a crucial international meeting in Italy. The meeting provided a f ..." |
 | | Targeted Therapies in Cancer Myth or Reality? (Advances in Experimental Medicine and Biology) by Francesco Colotta, Alberto Mantovani Hardcover, 191 Pages, Published 2007 by Springer ISBN-13: 978-0-387-73897-0, ISBN: 0-387-73897-5 "Billions of dollars are spent every year on research into targeted therapies for cancer. That's why it's more than ever crucial for the thousands of scientists working in the field to keep right up to date with the cutting edge. This fascinating collection of material goes a long way to helping them do so, featuring as it does contributions to a crucial international meeting in Italy. The meeting provided a f ..." |
 | | Challenges in Endocrine Disruptor Toxicology and Risk Assessment(1st Edition) (Issues in Toxicology): Volume 42 by Alberto Mantovani, Alexandra Fucic, Philip Marx-Stoelting Hardcover, 518 Pages, Published 2020 by Royal Society Of Chemistry, Cambridge ISBN-13: 978-1-78801-741-1, ISBN: 1-78801-741-2 "A. Kortenkamp, Ten years of mixing cocktails: A review of combination effects of endocrine-disrupting chemicals, Environ. Health Perspect., 2007, DOI: 10.1289/ehp.9357. 3. A. Kortenkamp, Low dose mixture effects of endocrine disrupters: ..." |
 | | Cellular and Cytokine Networks in Tissue Immunity 1990 Proceedings (Progress in Leukocyte Biology) by Monte S. Meltzer, Alberto Mantovani Hardcover, 386 Pages, Published 1991 by John Wiley & Sons Inc ISBN-13: 978-0-471-56097-5, ISBN: 0-471-56097-9 "This compilation examines the defensive role of cellular and cytokine networks responding to injury, infection or inflammation of different tissue, such as the brain, epithelium, intestinal tract and respiratory tract. It covers the complex actions of diverse cytokines, including human interleukin-9, interleukin-11, NADPH oxidase, human interferon-gamma receptor and interleukin-10." |
 | | Tumor-Associated Leukocytes Pathophysiology and Therapeutic Applications (Molecular Biology Intelligenc Unit) by Alberto Mantovani Hardcover, 106 Pages, Published 1994 by R G Landes Co ISBN-13: 978-1-57059-013-9, ISBN: 1-57059-013-3 ""Tumor-Associated Leukocytes" discusses leukocyte infiltration of neoplastic tissue. It also reviews the pathology and molecular mechanisms of leukocyte infiltration of tumours. Since tumour associated leukocytes are strategically located at the interface-between tumour and host, they represent targets for therapeutic intervention. Current therapeutic strategies and future prospects, including targeted cytokine immunotherapy, gene thera ..." |
 | | Macrophages(Reprint) Biology and Role in the Pathology of Diseases by Subhra K. Biswas, Alberto Mantovani Paperback, 615 Pages, Published 2016 by Springer ISBN-13: 978-1-4939-5487-2, ISBN: 1-4939-5487-3 "Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morpho ..." |
 | | Macrophages Biology and Role in the Pathology of Diseases by Subhra K. Biswas, Alberto Mantovani 615 Pages, Published 2014 by Springer ISBN-13: 978-1-4939-1311-4, ISBN: 1-4939-1311-5 "Sandra E. Nicholson and Peter J. Murray. 24.1. Introduction. What is macrophage polarization? How does STAT–Suppressors Of Cytokine Signaling (SOCS) signaling regulate polarization? The goal of this review is to summarize current knowledge pertinent to the second question. However, before we review the complex cytokine-driven processes that both promote and then feedback to inhibit polarization, we need to address the first questio ..." |
 | | Cancer Immunotherapy Chapter 27. Tumor-associated Macrophages in Cancer Growth and Progression by Alberto Mantovani, Maria Rosaria Galdiero, Paola Allavena, Antonio Sica 684 Pages, Published 2013 by Elsevier Inc. Chapters ISBN-13: 978-0-12-805923-4, ISBN: 0-12-805923-0 "VEGF is a potent angiogenic factor as well as a monocyte attractant that contributes to TAM recruitment. TAM promote angiogenesis and there is evidence that inhibition of TAM recruitment plays an important role in antiangiogenic strategies. We found that, in addition to VEGF, the angiogenic program established by hypoxia may rely also on the increased expression of CXCR4 by TAM and endothelial cells [138]. Intratumoral injection of ..." |
 | | Targeted Therapies in Cancer by Francesco Colotta, Alberto Mantovani 191 Pages, Published 2008 by Springer Science & Business Media ISBN-13: 978-0-387-73898-7, ISBN: 0-387-73898-3 "After Phase I and II studies had suggested important activity for Sunitinib in GIST patients failing Imatinib or being intolerant ... in a 2:1 randomization (Demetri, Van Oosterom, Garrett, Blackstein, Shah, Verweij, McArthur, Judson, Heinrich, Morgan, ... What the data on Sunitinib also show is that there may be a whole range of other options for treatment of GIST. ... Interestingly, this has not only lead to better results, but e ..." |
 | | Pharmacology of Cytokines by Alberto Mantovani, Petro Ghezzi, Charles A. Dinarello Hardcover, 329 Pages, Published 2000 by Oxford University Press ISBN-13: 978-0-19-850043-8, ISBN: 0-19-850043-2 "Cytokines are polypeptide mediators which act as communication signals among cells of the immune system as well as among other cells and tissues in the body. They are a heterogeneous and complex group and include interferons, tumor necrosis factor and chemokines. They play a key role in homeostasis and inhost defense and are involved in such inflammatory and autoimmune diseases such as rheumatoid arthritis as well as infectious diseases ..." |
 | | Reducing, Refining and Replacing the Use of Animals in Toxicity Testing(1st Edition) RSC (Issues in Toxicology) by Mike D. Waters, Dave Allen, Martin L. Stephens, Leslie Recio, Hao Zhu, Nathalie Alepee, Darrell R. Boverhof, John R. Fowle, Jon Richmond, Rodger Curren, David Basketter, Andreas Natsch, Charles Eldridge, Christopher J. Borgert, Errol Zeiger, Alberto Mantovani, Chantra Eskes, David Andrew, David G. Allen, Waters Allen Hardcover, 362 Pages, Published 2013 by Royal Society Of Chemistry ISBN-13: 978-1-84973-652-7, ISBN: 1-84973-652-9 "Toxicity testing is used to assess the safety or hazards presented by substances such as industrial chemicals, consumer products, and pharmaceuticals. At present, many methods involve laboratory animals. Alternative procedures, some involving human cell-based technologies, are now being developed which reduce, refine, or replace animal usage and minimize the pain and distress caused. These new tests must protect public health and the en ..." |
 | | Targeted Therapies in Cancer by Francesco Colotta, Alberto Mantovani Paperback, 191 Pages, Published 2008 by Springer ISBN-13: 978-0-387-52043-8, ISBN: 0-387-52043-0 "The text here offers readers an overview of diverse approaches, ranging from drug discovery to cellular therapy. Overall, the book addresses the key question of whether ultimately targeted therapy in cancer will be a myth or a reality." |
 | | Heterogeneity of Cancer Cells (Serono Symposia Publications) by Alberto Mantovani, Maurizio D'incalci, S. Garattini, Silvio Garattini Hardcover, 142 Pages, Published 1994 by Raven Pr ISBN-13: 978-0-88167-907-6, ISBN: 0-88167-907-0 |
 | | Challenges in Endocrine Disruptor Toxicology and Risk Assessment by Alberto Mantovani, Alexandra Fucic 539 Pages, Published 2020 by Royal Society Of Chemistry ISBN-13: 978-1-83916-083-7, ISBN: 1-83916-083-7 "Alberto Mantovani, Alexandra Fucic. CHAPTER 3 Issues for Hazard Characterization of Endocrine Disrupting Chemicals: The Use of Adverse Outcome Pathways ALBERTO MANTOVANI Department of Food safety, Nutrition and Veterinary public health ..." |
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